Anti-Canine CD5 PerCP-eFluor® 710

Description: This YKIX322.3 monoclonal antibody reacts with canine CD5, also known as Ly-1. CD5 is a 67-kDa type I transmembrane glycoprotein expressed on thymocytes and mature T cells. Studies have demonstrated that NK cells in dogs also express CD5, but at lower levels. In dogs, CD5 is not detectable on B cells or B cell lines.

References: Huang YC, Hung SW, Jan TR, Liao KW, Cheng CH, Wang YS, Chu RM. CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells. J Leukoc Biol. 2008 Dec;84(6):1501-10.

Rabanal RM, Ferrer L, Else RW. Immunohistochemical detection of canine leucocyte antigens by specific monoclonal antibodies in canine normal tissues. Vet Immunol Immunopathol. 1995 Jul;47(1-2):13-23.

Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994 Mar;43(3):137-54. (YKIX322.3, FC)