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Bone Biology

Bone biology and remodeling is an ongoing process that involves the functional integration of two processes, bone resorption and ossification, over the lifetime of an organism. Osteoclasts are responsible for bone resorption and are terminally differentiated multinucleated cells derived from the monocyte/macrophage lineage. The bone-forming cells responsible for ossification are osteoblasts which are differentiated from mesenchymal stem cells. Aberrant regulation of bone biology can result in a number of bone diseases, most notably osteoporosis.

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Name Clone Application Cat. No. Reg.  

Human BMP-2 Recombinant Protein

FA 14-8507 RUO

Human BMP-2 Recombinant Protein Carrier-Free

FA 34-8507 RUO

SAFE™ Human BMP-2 Recombinant Animal Free Protein

FA 68-8775 RUO

Anti-Human CD68 Biotin

eBioY1/82A (Y1/82A) FC 13-0689 RUO

Anti-Human CD68 FITC

eBioY1/82A (Y1/82A) FC 11-0689 RUO

Anti-Human CD68 PE

eBioY1/82A (Y1/82A) FC 12-0689 RUO

Anti-Human CD68 PE-Cyanine7

eBioY1/82A (Y1/82A) FC 25-0689 RUO

Anti-Human CD68 Purified

eBioY1/82A (Y1/82A) FC, IHC, IHC-F 14-0689 RUO

Anti-Mouse CD254 (RANK Ligand) Biotin

IK22/5 FC 13-5952 RUO

Anti-Mouse CD254 (RANK Ligand) PE

IK22/5 FC 12-5952 RUO

Anti-Mouse CD254 (RANK Ligand) Purified

IK22/5 FC, FA 14-5952 RUO

Anti-Mouse CD254 (RANK Ligand) Functional Grade Purified

IK22/5 FC, FA 16-5952 RUO

Anti-Human CD254 (RANK Ligand) Biotin

MIH24 FC, ELISA 13-6619 RUO

Anti-Human CD254 (RANK Ligand) PE

MIH24 FC 12-6619 RUO

Anti-Human CD254 (RANK Ligand) Purified

MIH24 FC, ELISA 14-6619 RUO

Anti-Mouse CD265 (RANK) Biotin

R12-31 FC 13-6612 RUO

Anti-Mouse CD265 (RANK) PE

R12-31 FC 12-6612 RUO

Anti-Mouse CD265 (RANK) Purified

R12-31 FC 14-6612 RUO

Anti-Human/Mouse GILZ PE

CFMKG15 FC, ICC 12-4033 RUO

Anti-Human/Mouse GILZ Purified

CFMKG15 FC, ICC, WB 14-4033 RUO

Human Osteocalcin Instant ELISA

ELISA BMS2020INST* RUO

Human Osteopontin Platinum ELISA

ELISA BMS2066* RUO

ProcartaPlex Human Osteopontin Simplex

Multiplex EPX01A-12066 RUO

Human Osteoprotegerin Instant ELISA

ELISA BMS2021INST* RUO

Mouse RANK Ligand Recombinant Protein

FA 14-8612 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents