Apoptosis

Apoptosis is a highly regulated and conserved pathway that plays a critical role in development and maintenance of cellular and tissue homeostasis. Cell death can occur via several pathways, including apoptosis, necrosis, and other “emerging” pathways which have become the focus of intense research. Classification of these types of cell death involves a defined set of morphological and/or biochemical criteria affecting the cellular architecture, and in the case of apoptosis, ultimately results in nuclear degradation and plasma membrane alterations.

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Name Clone Application Cat. No. Reg.  

Anti-Mouse/Rat TNF alpha eFluor® 660 (Alexa Fluor® 647 Replacement)

TN3-19 FC 50-7423 RUO

Anti-Mouse TNF alpha Cy5

MP6-XT22 FC 19-7321 RUO

Anti-Mouse TNF alpha APC

MP6-XT22 FC 17-7321 RUO

Anti-Mouse Perforin APC

eBioOMAK-D FC 17-9392 RUO

Anti-Mouse Granzyme B eFluor® 660 (Alexa Fluor® 647 Replacement)

NGZB FC 50-8898 RUO

Anti-Mouse Granzyme B Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Product Catalog number 50-8898)

16G6 FC 51-8822 RUO

Anti-Mouse Granzyme A APC

GzA-3G8.5 FC 17-5831 RUO

Anti-Mouse gp49 Receptor eFluor® 660 (Alexa® 647 Replacement)

H1.1 FC 50-5784 RUO

Anti-Human/Mouse Galectin-3 eFluor® 660 (Alexa Fluor® 647 Replacement)

eBioM3/38 (M3/38) FC 50-5301 RUO

Anti-Mouse CD279 (PD-1) APC

RMP1-30 FC 17-9981 RUO

Anti-Mouse CD279 (PD-1) APC

J43 FC 17-9985 RUO

Anti-Mouse CD95 (APO-1/Fas) APC

15A7 FC 17-0951 RUO

Anti-Mouse CD93 (AA4.1) APC

AA4.1 FC 17-5892 RUO

Anti-CD27 APC-eFluor® 780

LG.7F9 FC 47-0271 RUO

Anti-CD27 APC

LG.7F9 FC 17-0271 RUO

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FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents