Apoptosis

Apoptosis is a highly regulated and conserved pathway that plays a critical role in development and maintenance of cellular and tissue homeostasis. Cell death can occur via several pathways, including apoptosis, necrosis, and other “emerging” pathways which have become the focus of intense research. Classification of these types of cell death involves a defined set of morphological and/or biochemical criteria affecting the cellular architecture, and in the case of apoptosis, ultimately results in nuclear degradation and plasma membrane alterations.

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Name Clone Application Cat. No. Reg.  

Anti-Mouse CD95 (APO-1/Fas) Alexa Fluor® 488

15A7 FC 53-0951 RUO

Anti-Human PARP1 (Cleaved) Alexa Fluor® 488

HLNC4 FC 53-6668 RUO

Anti-Human TNF alpha Alexa Fluor® 488

MAb11 FC 53-7349 RUO

Anti-Mouse TNF alpha Alexa Fluor® 488

MP6-XT22 FC 53-7321 RUO

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FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents