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Angiogenesis is an important natural process for generation of new vasculature during embryonic development and in tissue or wound repair.  Angiogenic growth factors, including numerous cytokines, chemokines and growth factors, activate cells present in existing blood vessels to proliferate and form new vessels, as well as to release additional factors into the microenvironment.

While research around this process is important for diseases characterized by poor vascularisation, there is ever-increasing research on angiogenic processes in the development and support of tumorigenesis. Oncogenes can induce the release of angiogenic factors that recruit and reprogram other cells, induce cell differentiation, and establish a tumor microenvironment. Consequently, tumor tissues contain a large number of endothelial cells, fibroblasts and tumor-infiltrating-lymphocytes (TILs) that modulate the immune response in the microenvironment.

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Name Clone Application Cat. No. Reg.  

Anti-Acidic Cytokeratin Purified

AE1 ICC, IHC, IHC-F, IHC-P, WB 14-9001 RUO

Anti-Basic Cytokeratin Purified

AE3 ICC, IHC, IHC-F, IHC-P, WB 14-9000 RUO

Anti-Glial Fibrillary Acidic Protein (GFAP) Purified

GA5 FC, ICC, IHC, WB 14-9892 RUO

3 Item(s)

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25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents