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Angiogenesis

Angiogenesis is an important natural process for generation of new vasculature during embryonic development and in tissue or wound repair.  Angiogenic growth factors, including numerous cytokines, chemokines and growth factors, activate cells present in existing blood vessels to proliferate and form new vessels, as well as to release additional factors into the microenvironment.

While research around this process is important for diseases characterized by poor vascularisation, there is ever-increasing research on angiogenic processes in the development and support of tumorigenesis. Oncogenes can induce the release of angiogenic factors that recruit and reprogram other cells, induce cell differentiation, and establish a tumor microenvironment. Consequently, tumor tissues contain a large number of endothelial cells, fibroblasts and tumor-infiltrating-lymphocytes (TILs) that modulate the immune response in the microenvironment.

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Name Clone Application Cat. No. Reg.  

Human s90K/Mac-2BP Platinum ELISA

ELISA BMS234* RUO

Anti-Acidic Cytokeratin Purified

AE1 ICC, IHC, IHC-F, IHC-P, WB 14-9001 RUO

Human Activin A Protein Carrier-Free

FA 34-8993 RUO

Human Activin A Recombinant Protein

FA 14-8993 RUO

AKT 1 (Total) InstantOne™ ELISA

ELISA 85-86047 RUO

AKT (Total/Phospho) InstantOne™ ELISA

ELISA 85-86046 RUO

Anti-CD324 (E-Cadherin) eFluor® 660

DECMA-1 FC 50-3249 RUO

Anti-Basic Cytokeratin Purified

AE3 ICC, IHC, IHC-F, IHC-P, WB 14-9000 RUO

Anti-Human/Mouse beta-Catenin Alexa Fluor® 488

15B8 FC 53-2567 RUO

Anti-Human/Mouse beta-Catenin PE

15B8 FC 12-2567 RUO

Anti-Human/Mouse beta-Catenin Purified

15B8 FC, IHC, IHC-P, IP, WB 14-2567 RUO

Human BMP-2 Recombinant Protein

FA 14-8507 RUO

Human BMP-2 Recombinant Protein Carrier-Free

FA 34-8507 RUO

Anti-Mouse c-Met (HGF Receptor) FITC

eBioclone 7 FC 11-8854 RUO

Anti-Mouse c-Met (HGF Receptor) PE

eBioclone 7 FC 12-8854 RUO

Anti-Mouse c-Met (HGF Receptor) Purified

eBioclone 7 FC 14-8854 RUO

Anti-Human c-Met (HGF Receptor) Biotin

eBioclone 97 FC 13-8858 RUO

Anti-Human c-Met (HGF Receptor) FITC

eBioclone 97 FC 11-8858 RUO

Anti-Human c-Met (HGF Receptor) Purified

eBioclone 97 FC 14-8858 RUO

Anti-CCL2 (MCP-1) Biotin

2H5 ELISA 13-7096 RUO

Anti-CCL2 (MCP-1) FITC

2H5 FC 11-7096 RUO

Anti-CCL2 (MCP-1) Functional Grade Purified

2H5 FA 16-7096 RUO

Anti-CCL2 (MCP-1) PE

2H5 FC 12-7096 RUO

Anti-CCL2 (MCP-1) Purified

2H5 FC, ELISA, IHC, IHC-F, WB 14-7096 RUO

Anti-Mouse CCL2 (MCP-1) Purified

4E2 ELISA 14-7091 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents