Adaptive Immunity

Adaptive immunity is defined by the invocation of a specific cellular immune response, in contrast to innate immunity that is distinguished by a non-specific immunity.  Adaptive responses involve lymphocytes and are characterized two ways, humoral and cell-mediated immunity. B cells mediate a humoral response, the creation of antibodies to bind specifically to foreign antigens including bacteria, and microbial toxins. Cell-mediated immunity is a more complex system involving the production of cytotoxic T-lymphocytes, activated macrophages, activated NK cells, and cytokine release in response to an antigen and is mediated by T-lymphocytes. T cells recognize a pathogen only after antigens (small fragments of the pathogen) have been processed and presented typically in combination with a “self” receptor called a major histocompatibility complex (MHC) molecule. Cell-mediated immunity is important in combating intracellular organisms, performing tumor surveillance, mediating transplant rejection, and fighting fungal and viral infections.

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Name Clone Application Cat. No. Reg.  

Anti-Human SPI-B Purified

235D ICC, IHC, WB 14-9790 RUO

Anti-Human ACT1 Purified

9ACT12 WB 14-4040 RUO

Anti-Human/Mouse Activation-Induced Cytidine Deaminase (AID) Purified

mAID-2 IHC, WB 14-5959 RUO

Anti-Human/Mouse Activation-Induced Cytidine Deaminase (AID) Biotin

mAID-2 IHC, WB 13-5959 RUO

Anti-Human AHR Purified

FF3399 FC, ICC, IHC, WB 14-9854 RUO

Anti-Mouse Aiolos Purified

8B2 WB 14-5789 RUO

Anti-Human/Mouse Blimp1 Purified

6D3 IHC, WB 14-5963 RUO

Anti-Human Calcineurin Purified

BE2.1 WB 14-9894 RUO

Anti-Human/Non-Human Primate CD2 Purified

RPA-2.10 FC, IHC, FA, WB 14-0029 RUO

Anti-Rat CD3 Purified

eBioG4.18 (G4.18) FC, IHC, IP, WB 14-0030 RUO

Anti-Mouse CD3e Functional Grade Biotin

145-2C11 FC, IHC, FA, IP, WB 36-0031 RUO

Anti-Mouse CD3e Purified

145-2C11 FC, IHC, FA, IP, WB 14-0031 RUO

Anti-Human CD5 Purified

UCHT2 FC, IHC, WB 14-0059 RUO

Anti-Mouse CD6 Purified

IM348 FC, IHC, WB 14-0061 RUO

Anti-Rat CD8b Purified

eBio341 (341) FC, IHC, FA, IP, WB 14-0080 RUO

Anti-Human/Non-Human Primate CD8b Purified

SIDI8BEE FC, IP, WB 14-5273 RUO

Anti-Mouse CD20 Functional Grade Purified

AISB12 FC, FA, WB 16-0201 RUO

Anti-Mouse CD20 Purified

AISB12 FC, WB 14-0201 RUO

Anti-Human CD20 Purified

L26 IHC, IP, WB 14-0202 RUO

Anti-Mouse CD21/CD35 Purified

eBio8D9 (8D9) FC, FA, WB 14-0211 RUO

Anti-Mouse CD24 Purified

M1/69 FC, IHC, FA, WB 14-0242 RUO

Anti-Human CD28 Functional Grade Purified

CD28.6 FC, FA, WB 16-0288 RUO

Anti-Mouse CD39 Functional Grade Purified

24DMS1 FC, WB 16-0391 RUO

Anti-Mouse CD39 Purified

24DMS1 FC, WB 14-0391 RUO

anti-human CD40

3B2 ELISA, IHC, WB BMS197* RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents