Adaptive Immunity

Adaptive immunity is defined by the invocation of a specific cellular immune response, in contrast to innate immunity that is distinguished by a non-specific immunity.  Adaptive responses involve lymphocytes and are characterized two ways, humoral and cell-mediated immunity. B cells mediate a humoral response, the creation of antibodies to bind specifically to foreign antigens including bacteria, and microbial toxins. Cell-mediated immunity is a more complex system involving the production of cytotoxic T-lymphocytes, activated macrophages, activated NK cells, and cytokine release in response to an antigen and is mediated by T-lymphocytes. T cells recognize a pathogen only after antigens (small fragments of the pathogen) have been processed and presented typically in combination with a “self” receptor called a major histocompatibility complex (MHC) molecule. Cell-mediated immunity is important in combating intracellular organisms, performing tumor surveillance, mediating transplant rejection, and fighting fungal and viral infections.

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Name Clone Application Cat. No. Reg.  

Anti-Human CD8a PerCP-eFluor® 710

SK1 FC 46-0087 RUO

Anti-Canine CD8a PerCP-eFluor® 710

YCATE55.9 FC 46-5080 RUO

Anti-Mouse CD8b PerCP-eFluor® 710

eBioH35-17.2 (H35-17.2) FC 46-0083 RUO

Anti-Human CD19 PerCP-eFluor® 710

J3-129 FC 46-0197 RUO

Anti-Human CD19 PerCP-eFluor® 710

SJ25C1 FC 46-0198 RUO

Anti-Human CD21 PerCP-eFluor® 710

HB5 FC 46-0219 RUO

Anti-Mouse CD21/CD35 PerCP-eFluor® 710

eBio4E3 (4E3) FC 46-0212 RUO

Anti-Human CD22 PerCP-eFluor® 710

eBio4KB128 (4KB128) FC 46-0229 RUO

Anti-Mouse CD23 PerCP-eFluor® 710

B3B4 FC 46-0232 RUO

Anti-Human CD24 PerCP-eFluor® 710

eBioSN3 (SN3 A5-2H10) FC 46-0247 RUO

Anti-Mouse CD24 PerCP-eFluor® 710

M1/69 FC 46-0242 RUO

Anti-Human/Non-Human Primate CD25 PerCP-eFluor® 710

CD25-4E3 FC 46-0257 RUO

Anti-Rat CD25 PerCP-eFluor® 710

OX39 FC 46-0390 RUO

Anti-CD27 PerCP-eFluor® 710

LG.7F9 FC 46-0271 RUO

Anti-Human CD27 PerCP-eFluor® 710

O323 FC 46-0279 RUO

Anti-Mouse CD39 PerCP-eFluor® 710

24DMS1 FC 46-0391 RUO

Anti-Human CD39 PerCP-eFluor® 710

eBioA1 (A1) FC 46-0399 RUO

Anti-Mouse CD40 PerCP-eFluor® 710

1C10 FC 46-0401 RUO

Anti-Human CD40 PerCP-eFluor® 710

5C3 FC 46-0409 RUO

Anti-Human/Non-Human Primate CD43 PerCP-eFluor® 710

4-29-5-10-21 FC 46-0438 RUO

Anti-Human CD45 PerCP-eFluor® 710

HI30 FC 46-0459 RUO

Anti-Human/Mouse CD45R (B220) PerCP-eFluor® 710

RA3-6B2 FC 46-0452 RUO

Anti-Human/Non-Human Primate CD45RA PerCP-eFluor® 710

GRT22 FC 46-0468 RUO

Anti-Human CD45RO PerCP-eFluor® 710

UCHL1 FC 46-0457 RUO

Anti-Human CD46 PerCP-eFluor® 710

8E2 FC 46-0469 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents