Anti-Human CD95 (APO-1/Fas) Purified

Also known as: CD95, Fas receptor, APT 1, ALPS 1 A, TNFRSF6

Clone: 2R2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS198*

Cat. No. Size
BMS198 100 ug
Please inquire about custom configurations or bulk packaging.

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Description

Description: BMS198 specifically recognizes human APO-1/Fas. The antibody was purified from concentrated hybridoma tissue culture supernatant.

Details
Host Mouse
Isotype lgG3
Reactivity Human
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Functional Assays
Documentation
TDS Link Download TDS
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References

Citations: Fluhr,Herbert; Krenzer,Stefanie; Stein,Gerburg M.; Stork,Bjorn; Deperschmidt,Margarita; Wallwiener,Diethelm; Wesselborg,Sebastian; Zygmunt,Marek; Licht,Peter. Interferon-{gamma} and tumor necrosis factor-{alpha} sensitize primarily resistant human endometrial stromal cells to Fas-mediated apoptosis. Journal of Cell Science 2007;120:4126-4133. (Link)

Maeda,Hiroshi; Hori,Seiji; Nishitoh,Hideki; Ichijo,Hidenori; Ogawa,Osamu; Kakehi,Yoshiyuki; Kakizuka,Akira. Tumor Growth Inhibition by Arsenic Trioxide (As2O3) in the Orthotopic Metastasis Model of Androgen-independent Prostate Cancer. Cancer Research 2001;61:5432-5440. (Link)

Mahajan,Sandeep; Ghosh,Sutapa; Sudbeck,Elise A.; Zheng,Yaguo; Downs,Suzanne; Hupke,Michael; Uckun,Fatih M.. Rational Design and Synthesis of a Novel Anti-leukemic Agent Targeting Bruton's Tyrosine Kinase (BTK), LFM-A13 [alpha -Cyano-beta -Hydroxy-beta -Methyl-N-(2,5-Dibromophenyl)Propenamide]. Journal of Biological Chemistry 1999;274:9587-9599. (Link)

Vassilev,Alexei; Ozer,Zahide; Navara,Christopher; Mahajan,Sandeep; Uckun,Fatih M.. Bruton's Tyrosine Kinase as an Inhibitor of the Fas/CD95 Death-inducing Signaling Complex. Journal of Biological Chemistry 1999;274:1646-1656. (Link)

Scholz,Christian; Richter,Antje; Lehmann,Mario; Schulze-Osthoff,Klaus; Dorken,Bernd; Daniel,Peter. Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway. Oncogene 2005;24:7031-7042. (Link)