TGF beta 2
Alias: Transforming Growth Factor beta-2, TGFB2
TGFβ2 is a member of a superfamily of disulfide-linked homodimeric proteins secreted as latent proteins and stored at the cell surface and extracellular matrix. The bioactive TGFβ2 is released from a latent complex by proteolytic processing and conformation changes. TGFβ2 regulates cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. TGFβs is also involved in embryogenesis, tissue remodeling and wound healing. Functionally, human TGFβ2 can stimulate mouse cells.
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FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting
RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents