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ST2

Also known as IL-33 receptor (IL-33R, IL1R1), ST2 is a member of IL-1 receptor family.  In the membrane bound form, it consists of three extra-cellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain.  ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner.  IL-33/IL-33R interaction induces the production of Th2 cytokines.

ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33R/IL-33 interaction.

Expression of ST2 is noted in Th2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells and endothelial cells.  It is involved in host defense, allergy and inflammation. IL-33R/IL33 interaction has also been shown to be atheroprotective.

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13 Item(s)

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Name Clone Application Cat. No. Reg.  

Anti-Mouse ST2 (IL-33R) PerCP-eFluor® 710

RMST2-33 FC 46-9333 RUO

Anti-Mouse ST2 (IL-33R) APC

RMST2-33 FC 17-9333 RUO

Anti-Mouse ST2 (IL-33R) Biotin

RMST2-33 FC 13-9333 RUO

Anti-Mouse ST2 (IL-33R) Functional Grade Purified

RMST2-33 FC, FA 16-9333 RUO

ProcartaPlex Mouse ST2 (IL-33R) Simplex

Multiplex EPX01A-26047 RUO

Anti-Mouse ST2 (IL-33R) PE

RMST2-33 FC 12-9333 RUO

Anti-Mouse ST2 (IL-33R) Alexa Fluor® 488

RMST2-2 FC 53-9335 RUO

Anti-Mouse ST2 (IL-33R) Biotin

RMST2-2 FC 13-9335 RUO

Anti-Mouse ST2 (IL-33R) PE

RMST2-2 FC 12-9335 RUO

Anti-Mouse ST2 (IL-33R) PE-Cyanine7

RMST2-2 FC 25-9335 RUO

Anti-Mouse ST2 (IL-33R) PerCP-eFluor® 710

RMST2-2 FC 46-9335 RUO

Anti-Mouse ST2 (IL-33R) APC

RMST2-2 FC 17-9335 RUO

Mouse ST2 (IL-33R) ELISA Ready-SET-Go!

ELISA 88-9334 RUO

13 Item(s)

Set Descending Direction
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents