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This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).
DAQB-143M3.4; FLJ16302; hNotch4; Int3; Int-3; MGC74442; N4; neurogenic locus notch homolog protein 4; Notch 4; Notch 4 extracellular truncation; Notch 4 intracellular domain; Notch gene homolog 4; Notch homolog 4; notch receptor 4; NOTCH3; Notch4; putative Notch4 protein; Transforming protein Int-3
25 µg
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100 µL
100 µg
100 µg
100 µL
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100 µg
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