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IL-8

IL-8 is a member of the CXC chemokine family and is a major mediator of inflammatory response. IL-8 is induced by activators such as LPS, IL-1, and TNF to be produced/secrete from a variety of cell types that include monocytes, lymphocytes, granulocytes, fibroblasts, endothelial, and epithelial cells. IL-8 binds primarily to two GPCRs, CXCR1 and CXCR2, on neutrophils, monocytes, endothelial cells, astrocytes, and microglia. IL-8 functions as a strong chemoattractant and an angiogenic factor. Besides its chemotactic influence, IL-8 also triggers the secretion of superoxide anions and lysosomal enzymes in neutrophils. In basophils, IL-8 stimulates the histamine liberation. IL-8 selectively stimulates the ability of neutrophils and T-lymphocytes to invade injured or inflamed tissue. Other findings suggest that endothelial-derived IL-8 may function to attenuate inflammatory events at the interface between vessel wall and blood. IL-8 is also associated with a number diseases including rheumatoid arthritis, psoriasis, asthma, bladder cancer, blood incompatibility, contact dermatitis, graft rejection, inflammatory bowel disease, myocardial infarction, sepsis, and others.

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24 Item(s)

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Name Clone Application Cat. No. Reg.  

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex Porcine Cytokine & Chemokine Panel 1 (9 plex)

Multiplex EPX090-60829 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex NHP Cytokine/Chemokine/Growth Factor Panel (37 plex)

Multiplex EPX370-40045 RUO

Anti-Human IL-8 APC

8CH FC 17-8088 RUO

Anti-Human IL-8 eFluor® 450

8CH FC 48-8088 RUO

Anti-Human IL-8 PerCP-eFluor® 710

8CH FC 46-8088 RUO

Monkey IL-8 Instant ELISA

ELISA BMS640/3INST* RUO

Human IL-8 Instant ELISA

ELISA BMS204/3INSTCE* CE

Human IL-8 Instant ELISA

ELISA BMS204/3INST* RUO

Human IL-8/NAP-1 Matched Antibody Pairs

ELISA BMS204/3MST* RUO

Human IL-8 Platinum ELISA

ELISA BMS204/3CE* CE

Monkey IL-8 Platinum ELISA

ELISA BMS640/3* RUO

Human IL-8 Platinum ELISA

ELISA BMS204/3* RUO

Human IL-8 ELISA Ready-SET-Go!® (2nd Generation)

ELISA 88-8086 RUO

anti-human IL-8/FITC

NAP II FC BMS136FI* RUO

anti-human IL-8

NAP II FC, IHC BMS136* RUO

Platinum ProcartaPlex Human IL-8 (CXCL8) Simplex

Multiplex EPXP010-10204 RUO

ProcartaPlex Human IL-8 (CXCL8) Simplex

Multiplex EPX01A-10204 RUO

Human IL-8 Recombinant Protein

FA 14-8089 RUO

Human IL-8 Lyophilized Standard

ELISA 29-8089 RUO

ProcartaPlex Human Th1/Th2 & Chemokine Panel 1 (20 plex)

Multiplex EPX200-12173 RUO

ProcartaPlex Human Th9/Th17/Th22/Treg & Chemokine Panel 1 (16 plex)

Multiplex EPX160-12175 RUO

24 Item(s)

Set Descending Direction
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents