This site will redirect to thermofisher.com on April 7. Get details >


IL-31

IL-31 is a member of the gp130/IL-6 family of cytokines that is produced predominantly, but not exclusively, by activated TH2 cells. IL-31 binds to the heterodimeric receptor complex composed of IL-31RA (GPL) and oncostatin M receptor (OSMR). This receptor complex is expressed constitutively on keratinocytes and epithelial cells and can be upregulated on monocytes by IFNγ or LPS. IL-31 signaling activates the JAK/STAT, PI3 kinase/AKT, and MAP kinase pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles including regulation of hematopoiesis and immune response. IL-31 is associated with the promotion of allergic and chronic inflammatory conditions such as dermatitis, pruritus, airway hyper-sensititvity and inflammatory bowel disease.

Suggest a new product or place a custom order.

19 Item(s)

Set Descending Direction
25 | 50
Name Clone Application Cat. No. Reg.  

ProcartaPlex Human Cytokine 1C & Chemokine Panel 1 (16 plex)

Multiplex EPX160-12176 RUO

ProcartaPlex Human Cytokine Panel 1B (25 plex)

Multiplex EPX250-12166 RUO

ProcartaPlex Human Cytokine Panel 1C (7 plex)

Multiplex EPX070-10010 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Convenience Panel 1 (45 plex)

Multiplex EPXR450-12171 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Panel 1 (45 plex)

Multiplex EPX450-12171 RUO

ProcartaPlex Mouse Cytokine Panel 1B (10 plex)

Multiplex EPX100-26091 RUO

Anti-Human IL-31 eFluor® 660

31SNEZE FC 50-9319 RUO

Mouse IL-31 Platinum ELISA

ELISA BMS6030* RUO

Human IL-31 Platinum ELISA

ELISA BMS2041* RUO

ProcartaPlex Mouse IL-31 Simplex

Multiplex EPX01A-26030 RUO

ProcartaPlex Human IL-31 Simplex

Multiplex EPX01A-12041 RUO

ProcartaPlex Human 45plex Control Set

Multiplex EPX450-12171* RUO

ProcartaPlex Mouse 36plex Control Set

Multiplex EPX360-26092* RUO

ProcartaPlex Human Th1/Th2 & Cytokine Panel 1C (18 plex)

Multiplex EPX180-12172 RUO

ProcartaPlex Human Th9/Th17/Th22/Treg & Cytokine Panel 1C (14 plex)

Multiplex EPX140-12174 RUO

19 Item(s)

Set Descending Direction
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents