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IL-22

Alias: Interleukin-22,TIF, IL-10-related T cell-derived inducible factor

IL-22 is a cytokine that regulates the production of acute phase proteins of the immunological response. IL-22 is produced by TH1, TH17, and NK cells acting primarily on epithelial cells and is involved in inflammatory responses. On binding to its receptor (IL-22R1), which is associated to the interleukin-10 receptor 2 (IL-10R2), IL-22 promotes activation of multiple signals including the STAT1, STAT3, ERK, p38, and JNK pathways. IL-22BP, a soluble receptor, that able to bind to IL-22 as an antagonist is thought to provide systemic regulation of IL-22 activity. Interestingly, neither resting nor activated immune cells express IL-22 receptor, nor does it have any effect on these cells in vitro and in vivo. IL-22 is believed to act more on skin cells and cells of the digestive and respiratory systems. IL-22 serves as a protective molecule to counteract the destructive nature of the immune response to limit tissue damage and acts as a T cell mediator that directly promotes the innate, nonspecific immunity of tissues.

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Name Clone Application Cat. No. Reg.  

ProcartaPlex Human Cytokine Panel 1B (25 plex)

Multiplex EPX250-12166 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Panel 1 (45 plex)

Multiplex EPX450-12171 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Convenience Panel 1 (45 plex)

Multiplex EPXR450-12171 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1 (26 plex)

Multiplex EPX260-26088 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1 (26 plex)

Multiplex EPXR260-26088 RUO

eZKine™ Th17/Th22 Whole Blood Intracellular Cytokine Kit

FC 8822-6853 RUO

Anti-Mouse IL-22 PE

1H8PWSR FC 12-7221 RUO

Anti-Mouse IL-22 PerCP-eFluor® 710

1H8PWSR FC 46-7221 RUO

Anti-Human IL-22 eFluor® 450

22URTI FC 48-7229 RUO

Anti-Human IL-22 eFluor® 660

22URTI FC 50-7229 RUO

Anti-Human IL-22 FITC

22URTI FC 11-7229 RUO

Anti-Human IL-22 PE

22URTI FC 12-7229 RUO

Anti-Human IL-22 PE-Cyanine7

22URTI FC 25-7229 RUO

Anti-Human IL-22 PerCP-eFluor® 710

22URTI FC 46-7229 RUO

Human IL-22 Platinum ELISA

ELISA BMS2047* RUO

Mouse IL-22 Platinum ELISA

ELISA BMS6022* RUO

Mouse IL-22 ELISA Ready-SET-Go!®

ELISA 88-7422 RUO

Human IL-22 ELISA Ready-SET-Go!®

ELISA 88-7522 RUO

Human IL-22 Single-Use RSG ELISA Standard

ELISA 39-8230 RUO

Anti-Human/Mouse IL-22 APC

IL22JOP FC 17-7222 RUO

Anti-Human/Mouse IL-22 Functional Grade Purified

IL22JOP FA 16-7222 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents