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IL-17AF

IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (TH17) cells, γδ T cells, and several subsets of innate lymphoid cells. Somewhat less appreciated is that IL-17A and IL-17F subunits can also form the heterodimer IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis. IL-17AF functions are believed to be similar to both IL-17A and IL-17F with autoimmunity pathology and neutrophil recruitment and immunity to extracellular pathogens. Please review IL-17A and IL-17F for additional information.

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12 Item(s)

Set Descending Direction
25 | 50
Name Clone Application Cat. No. Reg.  

Anti-Mouse IL-17AF PE

B8KN8R FC 12-9171 RUO

Mouse IL-17AF (heterodimer) ELISA Ready-SET-Go! (2nd Generation)

ELISA ELISA 88-8711 RUO

Human IL-17AF Platinum ELISA

ELISA BMS2082* RUO

Mouse IL-17AF Platinum ELISA

ELISA BMS6026* RUO

Human IL-17AF (heterodimer) ELISA Ready-SET-Go!®

ELISA 88-7117 RUO

ProcartaPlex Human IL-17AF Simplex

Multiplex EPX01A-12082 RUO

Mouse IL-17AF (heterodimer) Single-Use ELISA RSG Standard Recombinant

ELISA 39-8172 RUO

Anti-Mouse IL-17AF eFluor® 660

B8KN8R FC 50-9171 RUO

Anti-Human IL-17AF eFluor® 450

20LJS09 FC 48-9179 RUO

Anti-Human IL-17AF FITC

20LJS09 FC 11-9179 RUO

Anti-Human IL-17AF PE

20LJS09 FC 12-9179 RUO

Human IL-17AF Single-Use ELISA RSG Standard

ELISA 39-8236 RUO

12 Item(s)

Set Descending Direction
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents