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IL-13

Alias: Interleukin-13, NC3

IL-13 is a pleiotropic TH2 cytokine expressed by activated T helper cells, CD8+ T cells, and NK cells. IL-13 functions to suppress macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 binds to the receptor complex IL-13R composed of IL-4Rα and IL-13Rα1, that it shares with IL-4, on various cell types that include mononuclear phagocytes and large granular lymphocytes B cells. IL-13 induces CD23 expression on B cells, promotes B cell proliferation in combination with anti-Ig or CD40 antibodies, and stimulates secretion IgE, and IgG4. IL-13 has also been shown to prolong survival of human monocytes and increases surface expression of MHC class II and members of the integrin superfamily, like CD11b, CD11c, CD18, CD29 and CD49e, and induces IFNγ production by NK cells. IL-13 also inhibits the production of a series of cytokines that include IL-1, IL-6, IL-8, and TNFα by activated human monocytes. As a biomarker, the measurement of IL-13 in body fluids may thus provide further information about the pathophysiology of atopic diseases and is known to play a central role in the pathogenesis of asthma.

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Name Clone Application Cat. No. Reg.  

Anti-Human IL-13 PE

85BRD FC 12-7136 RUO

ProcartaPlex Human Cytokine Panel 1B (25 plex)

Multiplex EPX250-12166 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex NHP Cytokine/Chemokine/Growth Factor Panel (37 plex)

Multiplex EPX370-40045 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Panel 1 (45 plex)

Multiplex EPX450-12171 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Convenience Panel 1 (45 plex)

Multiplex EPXR450-12171 RUO

ProcartaPlex Rat Cytokine & Chemokine Panel (22 plex)

Multiplex EPX220-30122 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1 (26 plex)

Multiplex EPX260-26088 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1 (26 plex)

Multiplex EPXR260-26088 RUO

ProcartaPlex Mouse IL-3 Simplex

Multiplex EPX01A-26035 RUO

anti-human IL-13/FITC

B-P6 FC BMS133FI* RUO

anti-human IL-13

B-P6 FA BMS133* RUO

Anti-Mouse IL-13 Biotin

eBio1316H ELISA 13-7135 RUO

Anti-Mouse IL-13 Functional Grade Purified

eBio1316H FA 16-7135 RUO

Anti-Mouse IL-13 PE-Cyanine7

eBio13A FC 25-7133 RUO

Anti-Mouse IL-13 Alexa Fluor® 488

eBio13A FC 53-7133 RUO

Anti-Mouse IL-13 eFluor® 450

eBio13A FC 48-7133 RUO

Anti-Mouse IL-13 eFluor® 660

eBio13A FC 50-7133 RUO

Anti-Mouse IL-13 Functional Grade Purified

eBio13A ELISA 16-7133 RUO

Anti-Mouse IL-13 PE

eBio13A FC 12-7133 RUO

Anti-Mouse IL-13 PE-eFluor® 610

eBio13A FC 61-7133 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents