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IL-1 alpha

Alias: IL-1α, Interleukin-1 alpha, IL1F1, Hematopoietin-1

IL-1α is a pro-inflammatory cytokine that affects T-helper cells causing the induction of IL-2 secretion and the expression of IL-2 receptors, as well as causing B cells to promote cell proliferation and immunoglobulin synthesis. IL-1α is present in various biological fluids and the monitoring its levels is a valuable biomarker. Elevated serum or blood levels of IL-1α have been found in of several carcinomas such as head and neck cancer, pancreatic cancer and thyroid cancer, in experimental acute pyelonephritis, in acute viral hepatitis and in septic shock. Both elevations in serum levels and joint fluids (synovial fluids) are detected in rheumatoid arthritis. Increased plasma and CSF levels are found in patients with schizophrenia. Significantly elevated concentrations in gingival cervical fluid in subjects with peridantitis are detected. Urinary levels of IL-1α correspond to disease and therapy response in bladder cancer.

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Name Clone Application Cat. No. Reg.  

ProcartaPlex Human Cytokine 1C & Chemokine Panel 1 (16 plex)

Multiplex EPX160-12176 RUO

ProcartaPlex Human Cytokine Panel 1B (25 plex)

Multiplex EPX250-12166 RUO

ProcartaPlex Human Cytokine Panel 1C (7 plex)

Multiplex EPX070-10010 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Convenience Panel 1 (45 plex)

Multiplex EPXR450-12171 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Panel 1 (45 plex)

Multiplex EPX450-12171 RUO

ProcartaPlex Rat Cytokine & Chemokine Panel (22 plex)

Multiplex EPX220-30122 RUO

ProcartaPlex Mouse Cytokine Panel 1B (10 plex)

Multiplex EPX100-26091 RUO

Anti-Human IL-1 alpha FITC

364/3B3-14 FC 11-7118 RUO

Anti-Human IL-1 alpha Purified

364/3B3-14 FC, ELISA 14-7118 RUO

Anti-Mouse IL-1 alpha Functional Grade Purified

ALF-161 ELISA, FA 16-7011 RUO

Anti-Mouse IL-1 alpha PE

ALF-161 FC 12-7011 RUO

Anti-Mouse IL-1 alpha Purified

ALF-161 ELISA 14-7011 RUO

Rat IL-1 alpha Platinum ELISA

ELISA BMS627* RUO

Human IL-1alpha Platinum ELISA

ELISA BMS243/2CE* CE

Mouse IL-1alpha Platinum ELISA

ELISA BMS611* RUO

Human IL-1alpha Platinum ELISA

ELISA BMS243/2* RUO

Platinum ProcartaPlex Human IL-1 alpha Simplex

Multiplex EPXP010-10243 RUO

ProcartaPlex Mouse IL-1 alpha Simplex

Multiplex EPX01A-20611 RUO

ProcartaPlex Rat IL-1 alpha Simplex

Multiplex EPX01A-30611 RUO

ProcartaPlex Human IL-1 alpha Simplex

Multiplex EPX01A-10243 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents