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IFN gamma

Alias: Interferon gamma, IFNγ, IFNG

IFNγ (Type II interferon) is a homodimeric glycoprotein that is produced by activated T, B and NK cells. IFNγ is produced during infection by cytotoxic T cells (CD8+) and by TH1 cells where it preferentially inhibits the proliferation of TH2, resulting in the preferential proliferation of TH1 cells. IFNγ functions as an anti-viral and anti-parasitic agent and also acts in synergy with other cytokines, such as TNFα to inhibit the proliferation of normal and transformed cells. IFNγ induces immunomodulatory effects on a wide range of cell types that includes being a potent activator of mononuclear phagocytes, augmentation of endocytosis and phagocytosis by monocytes, and activation of macrophages to kill tumor cells. Additionally, it enhances the proliferation of activated B cells and can act synergistically with IL-2 to increase immunoglobulin light-chain synthesis. Finally, IFNγ activates neutrophils, NK cells and vascular endothelial cells. The role of IFNγ as a disease marker has been demonstrated for a number of different pathological situations including infections, autoimmune diseases, transplant rejection, allergy, and diabetes.

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Name Clone Application Cat. No. Reg.  

ProcartaPlex Human Cytokine Panel 1B (25 plex)

Multiplex EPX250-12166 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Porcine Cytokine & Chemokine Panel 1 (9 plex)

Multiplex EPX090-60829 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex Canine Cytokine/Chemokine/Growth Factor Panel 1 (11 plex)

Multiplex EPX11A-50511 RUO

ProcartaPlex NHP Cytokine/Chemokine/Growth Factor Panel (37 plex)

Multiplex EPX370-40045 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Convenience Panel 1 (45 plex)

Multiplex EPXR450-12171 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Panel 1 (45 plex)

Multiplex EPX450-12171 RUO

ProcartaPlex Rat Cytokine & Chemokine Panel (22 plex)

Multiplex EPX220-30122 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1 (26 plex)

Multiplex EPXR260-26088 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1 (26 plex)

Multiplex EPX260-26088 RUO

eZKine™ 4-Color Compensation Control Kit

FC 8822-6856 RUO

eZKine™ CD8 Activation 1 Whole Blood Intracellular Cytokine Kit

FC 8822-6854 RUO

eZKine™ CD8 Activation 2 Whole Blood Intracellular Cytokine Kit

FC 8822-6855 RUO

eZKine™ Th1 Activation 1 Whole Blood Intracellular Cytokine Kit

FC 8822-6851 RUO

eZKine™ Th1 Activation 2 Whole Blood Intracellular Cytokine Kit

FC 8822-6852 RUO

eZKine™ Th1/Th17 Whole Blood Intracellular Cytokine Kit

FC 8822-6850 RUO

ProcartaPlex Mouse High Sensitivity Panel (5 plex)

Multiplex EPXS050-22199 RUO

ProcartaPlex Human High Sensitivity Panel (9 plex)

Multiplex EPXS090-12199 RUO

Anti-Human IFN gamma Alexa Fluor® 488

4S.B3 FC 53-7319 RUO

Anti-Human IFN gamma Alexa Fluor® 700

4S.B3 FC 56-7319 RUO

Anti-Human IFN gamma APC

4S.B3 FC 17-7319 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents