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G-CSF

Alias: Granulocyte Colony-Stimulating Factor, CSF3

G-CSF is a member of the IL-6 cytokine family. G-CSF is produced by activated monocytes, macrophages, endothelial cells, fibroblasts, astrocytes, and osteoblasts in response to infection and inflammatory mediators such as IL-1β, IL-17, TNFα, and LPS, as well as various transformed cells such as carcinoma cells and myeloblastic leukemia cells. G-CSF has been shown to have specific effects on the proliferation, differentiation, and activation of hematopoietic cells. G-CSF binding activates the JAK/STAT signaling pathway that results in the activation and mobilization of granulocytic precursors from the bone marrow and supports the proliferation, activation, and differentiation of neutrophils in the blood. Clinically, the use of G-CSF has been approved for several therapeutical applications including the treatment of neonatal infections, therapy of acute myocardial infarction, therapy in chronic autoimmune neutropenia, treatment of acute myeloid leukemias, Sweet’s syndrome, and AIDS. G-CSF has further been shown to be a marker protein for different carcinomas such as bladder cancer. (34, 75)

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22 Item(s)

Set Descending Direction
25 | 50
Name Clone Application Cat. No. Reg.  

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex NHP Cytokine/Chemokine/Growth Factor Panel (37 plex)

Multiplex EPX370-40045 RUO

ProcartaPlex Rat Cytokine & Chemokine Panel (22 plex)

Multiplex EPX220-30122 RUO

ProcartaPlex NHP Cytokine Panel 1b (6 plex)

Multiplex EPX060-40042 RUO

ProcartaPlex Mouse Cytokine Panel 1B (10 plex)

Multiplex EPX100-26091 RUO

Anti-Human G-CSF Functional Grade Purified

4A4RC FA 16-7338 RUO

Anti-Human G-CSF eFluor® 660

8F5CSF FC 50-7351 RUO

Anti-Human G-CSF PE

8F5CSF FC 12-7351 RUO

Human G-CSF Instant ELISA

ELISA BMS2001INST* RUO

Human G-CSF Instant ELISA

ELISA BMS2001INSTCE* CE

Recombinant Human G-CSF

BMS322* RUO

Recombinant Mouse G-CSF

BMS323* RUO

ProcartaPlex Human G-CSF (CSF-3) Simplex

Multiplex EPX01A-12001 RUO

ProcartaPlex NHP G-CSF (CSF-3) Simplex

Multiplex EPX01A-42001 RUO

ProcartaPlex Mouse G-CSF (CSF-3) Simplex

Multiplex EPX01A-26034 RUO

ProcartaPlex Rat G-CSF (CSF-3) Simplex

Multiplex EPX01A-36034 RUO

Anti-Mouse G-CSF eFluor® 660

9B4CSF FC 50-7353 RUO

Anti-Mouse G-CSF Functional Grade Purified

9B4CSF FA 16-7353 RUO

ProcartaPlex Mouse 36plex Control Set

Multiplex EPX360-26092* RUO

ProcartaPlex Rat Th Complete Panel (14plex)

Multiplex EPX140-30120 RUO

22 Item(s)

Set Descending Direction
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents