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CCL4 (MIP-1 beta)

Alias: MIP-1β, C-C motif chemokine 4, Macrophage Inflammatory Protein 1-beta

MIP-1β is a member of the CC-subfamily of chemokines and is most closely related to MIP-1α (CCL3). These proteins play critical roles in the recruitment of leukocytes to the site of inflammation and signal through CCR1, CCR4, and CCR5. MIP-1α and MIP-1β are involved in response to their affects on cellular and humoral immune response. MIP-1α stimulates strong antigen specific responses, while MIP-1β promotes antibody responses. While both CCL3 and CCL4 are both chemoattractant for monocytes, macrophages, and dendritic cells, they differ in there responses with T cells. While MIP-1α preferentially attracts CD8+ T cells, CD4+ T cells are more responsive to MIP-1β. MIP-1 protein expression levels has been shown to be important regarding numerous diseases such as multiple myeloma, asthmatic disorders, EAE, HIV, and sepsis.

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Name Clone Application Cat. No. Reg.  

Human CCL4 (MIP-1 beta) Single-Use RSG ELISA Standard

ELISA 39-8265 RUO

Anti-Human CCL4 (MIP-1 beta) APC

FL34Z3L FC 17-7540 RUO

Anti-Human CCL4 (MIP-1 beta) PerCP-eFluor® 710

FL34Z3L FC 46-7540 RUO

Human CCL4 (MIP-1 beta) ELISA Ready-SET-Go!

ELISA 88-7034 RUO

ProcartaPlex Human Chemokine Panel 1 (9 plex)

Multiplex EPX090-12187 RUO

ProcartaPlex NHP Chemokine Panel (10 plex)

Multiplex EPX100-40041 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex NHP Cytokine/Chemokine/Growth Factor Panel (37 plex)

Multiplex EPX370-40045 RUO

ProcartaPlex Human Inflammation Panel (20 plex)

Multiplex EPX200-12185 RUO

Platinum ProcartaPlex Human MIP-1 beta (CCL4) Simplex

Multiplex EPXP010-12030 RUO

ProcartaPlex Human MIP-1 beta (CCL4) Simplex

Multiplex EPX01A-12030 RUO

Platinum ProcartaPlex Human Panel 1 (42 plex)

Multiplex EPXP420-10200 RUO

Platinum ProcartaPlex Human 42plex Control Set

Multiplex EPXP420-10200* RUO

13 Item(s)

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25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents