CCL20 (MIP-3 alpha)
Alias: MIP-3α, C-C motif chemokine 20, Macrophage Inflammatory Protein 3 alpha
MIP-3α is a cytokine belonging to the CC chemokine family. MIP-3α is strongly upregulated by inflammatory signals such as TNF and IFNγ and downregulated by the anti-inflammatory cytokine IL-10 in various cell types and tissues such as lyphocytes, lymph node, and the liver. MIP-3α acts as a chemoattractant for lymphocytes and elicits its functions on its target cell by binding to the chemokine receptor CCR6.