CCL20 (MIP-3 alpha)
Alias: MIP-3α, C-C motif chemokine 20, Macrophage Inflammatory Protein 3 alpha
MIP-3α is a cytokine belonging to the CC chemokine family. MIP-3α is strongly upregulated by inflammatory signals such as TNF and IFNγ and downregulated by the anti-inflammatory cytokine IL-10 in various cell types and tissues such as lyphocytes, lymph node, and the liver. MIP-3α acts as a chemoattractant for lymphocytes and elicits its functions on its target cell by binding to the chemokine receptor CCR6.
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FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting
RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents