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CCL2 (MCP-1)

Alias: Monocyte Chemotactic Protein 1, C-C motif chemokine 2

MCP-1 is a member of the ß (CC) subfamily of chemokines. MCP-1 is mainly expressed by macrophages in response to a wide range of cytokines that include IL-1β, IL-6, and TNFα, but can also be produced by a variety of other cells and tissues, such as fibroblasts, endothelial cells, or certain tumor cells. MCP-1 functions as a chemoattractant protein for monocytes, T lymphocytes, and NK cells where it helps to regulate their adhesion molecule and cytokine expression patterns. MCP-1 has also been shown to activate monocytes to be cytostatic for some human tumor cell lines and attracting, activating, and inducing basophils to release histamine. Elevated levels of MCP-1 have also been found in connection with inflammation, Alzheimer’s disease (AD), myocardial ischemia, and viral infections.

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Name Clone Application Cat. No. Reg.  

Anti-CCL2 (MCP-1) Biotin

2H5 ELISA 13-7096 RUO

Anti-CCL2 (MCP-1) FITC

2H5 FC 11-7096 RUO

Anti-CCL2 (MCP-1) Functional Grade Purified

2H5 FA 16-7096 RUO

Anti-CCL2 (MCP-1) PE

2H5 FC 12-7096 RUO

Anti-CCL2 (MCP-1) Purified

2H5 FC, ELISA, IHC, IHC-F, WB 14-7096 RUO

Anti-Mouse CCL2 (MCP-1) Purified

4E2 ELISA 14-7091 RUO

Anti-Human CCL2 (MCP-1) APC

5D3-F7 FC 17-7099 RUO

Anti-Human CCL2 (MCP-1) PE

5D3-F7 FC 12-7099 RUO

Anti-Human CCL2 (MCP-1) Purified

5D3-F7 FC, ELISA, IHC, IHC-P, IP 14-7099 RUO

Human CCL2 (MCP-1) Single-Use ELISA RSG Standard

ELISA 39-7399 RUO

Mouse CCL2 (MCP-1) Single-Use ELISA RSG Standard

ELISA 39-7391 RUO

Human CCL2 (MCP-1) ELISA Ready-SET-Go!®

ELISA 88-7399 RUO

Mouse CCL2 (MCP-1) ELISA Ready-SET-Go!®

ELISA 88-7391 RUO

Human CCL2 (MCP-1) Recombinant Protein

FA 14-8398 RUO

ProcartaPlex Human Chemokine Panel 1 (9 plex)

Multiplex EPX090-12187 RUO

ProcartaPlex Mouse Chemokine Panel 1 (9 plex)

Multiplex EPX090-20821 RUO

ProcartaPlex NHP Chemokine Panel (10 plex)

Multiplex EPX100-40041 RUO

ProcartaPlex Rat Chemokine Panel (8 plex)

Multiplex EPX080-30121 RUO

ProcartaPlex Human Cytokine 1C & Chemokine Panel 1 (16 plex)

Multiplex EPX160-12176 RUO

ProcartaPlex Mouse Cytokine & Chemokine Panel 1A (36 plex)

Multiplex EPX360-26092 RUO

ProcartaPlex Mouse Cytokine & Chemokine Convenience Panel 1A (36 plex)

Multiplex EPXR360-26092 RUO

ProcartaPlex Human Cytokine & Chemokine Convenience Panel 1A (34 plex)

Multiplex EPXR340-12167 RUO

ProcartaPlex Human Cytokine & Chemokine Panel 1A (34 plex)

Multiplex EPX340-12167 RUO

ProcartaPlex NHP Cytokine & Chemokine Panel (30 plex)

Multiplex EPX300-40044 RUO

ProcartaPlex Canine Cytokine/Chemokine/Growth Factor Panel 1 (11 plex)

Multiplex EPX11A-50511 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents