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Brain-Derived Neurotrophic Factor (BDNF)

BDNF is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, proBDNF is biologically active and is secreted from synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system where it acts in an autocrine and paracrine manner on several classes of neurons. BDNF signaling occurs mainly through the receptor tyrosine kinase TrkB, although binding to the lower-affinity receptor p75NTR has also been demonstrated. Functionally, BDNF promotes neuronal survival and differentiation, it is involved in axonal growth and dendritic growth and morphology, and it is known to be a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. Additionally, BDNF has been shown to play a critical role in memory formation and synaptic regulation.

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13 Item(s)

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Name Clone Application Cat. No. Reg.  

Human BDNF Recombinant Protein Purified

FA 14-8366 RUO

Platinum ProcartaPlex Human BDNF Simplex

Multiplex EPXP010-12116 RUO

ProcartaPlex NHP BDNF Simplex

Multiplex EPX01A-42116 RUO

ProcartaPlex Human BDNF Simplex

Multiplex EPX01A-12116 RUO

ProcartaPlex NHP Cytokine/Chemokine/Growth Factor Panel (37 plex)

Multiplex EPX370-40045 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Panel 1 (45 plex)

Multiplex EPX450-12171 RUO

ProcartaPlex Human Cytokine/Chemokine/Growth Factor Convenience Panel 1 (45 plex)

Multiplex EPXR450-12171 RUO

ProcartaPlex Human Growth Factor Panel (11plex)

Multiplex EPX110-12170 RUO

ProcartaPlex NHP Growth Factor Panel (7 plex)

Multiplex EPX070-40043 RUO

ProcartaPlex Human Myokine Panel (8 plex)

Multiplex EPX080-12186 RUO

Platinum ProcartaPlex Human Panel 1 (42 plex)

Multiplex EPXP420-10200 RUO

Platinum ProcartaPlex Human 42plex Control Set

Multiplex EPXP420-10200* RUO

ProcartaPlex Human 45plex Control Set

Multiplex EPX450-12171* RUO

13 Item(s)

Set Descending Direction
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents